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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
29.7
Human Site:
Y1257
Identified Species:
40.83
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
Y1257
W
K
N
F
A
E
L
Y
E
S
F
Q
N
P
K
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
Y1257
W
K
N
F
A
E
L
Y
E
S
F
Q
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
Y1252
W
K
N
F
A
E
L
Y
E
S
F
Q
N
P
K
Dog
Lupus familis
XP_532459
1267
140567
Y1241
W
K
N
F
A
E
L
Y
E
N
F
Q
N
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
Y1258
G
K
E
F
A
E
L
Y
E
N
F
Q
N
P
K
Rat
Rattus norvegicus
P46462
806
89330
A781
P
S
G
N
Q
G
G
A
G
P
S
Q
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
Y1151
W
K
T
F
T
E
L
Y
D
N
F
Q
N
P
R
Chicken
Gallus gallus
XP_418655
1290
143066
Y1265
W
K
N
F
T
E
L
Y
D
N
F
Q
N
P
K
Frog
Xenopus laevis
P23787
805
89193
G780
F
P
A
G
G
Q
S
G
A
G
P
S
P
G
A
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
S781
P
S
S
N
Q
G
G
S
G
P
S
Q
G
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
T776
N
F
R
F
P
G
Q
T
G
N
T
S
G
S
G
Honey Bee
Apis mellifera
XP_397107
1069
120490
A1044
V
C
A
E
V
L
L
A
R
L
W
E
V
L
S
Nematode Worm
Caenorhab. elegans
P54812
810
89622
G785
G
N
N
F
K
F
P
G
E
A
P
S
A
G
Q
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
Y1482
R
Q
K
Y
R
Q
I
Y
K
S
F
V
K
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
G790
G
T
T
G
A
F
P
G
A
A
A
T
V
G
G
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
R1018
K
L
R
G
I
Y
D
R
F
Q
K
D
R
N
G
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
G1346
K
K
D
G
K
G
K
G
K
A
A
D
N
E
V
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
100
93.3
N.A.
80
6.6
N.A.
66.6
80
0
6.6
N.A.
6.6
6.6
20
20
P-Site Similarity:
100
100
100
100
N.A.
86.6
6.6
N.A.
86.6
93.3
13.3
13.3
N.A.
13.3
20
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
0
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
36
0
0
12
12
18
12
0
6
0
6
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
0
6
0
12
0
0
12
0
0
0
% D
% Glu:
0
0
6
6
0
42
0
0
36
0
0
6
0
6
0
% E
% Phe:
6
6
0
53
0
12
0
0
6
0
48
0
0
0
0
% F
% Gly:
18
0
6
24
6
24
12
24
18
6
0
0
18
18
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
6
0
6
0
0
0
0
0
0
0
0
% I
% Lys:
12
48
6
0
12
0
6
0
12
0
6
0
6
0
36
% K
% Leu:
0
6
0
0
0
6
48
0
0
6
0
0
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
36
12
0
0
0
0
0
30
0
0
48
6
0
% N
% Pro:
12
6
0
0
6
0
12
0
0
12
12
0
6
42
0
% P
% Gln:
0
6
0
0
12
12
6
0
0
6
0
53
0
0
6
% Q
% Arg:
6
0
12
0
6
0
0
6
6
0
0
0
6
0
12
% R
% Ser:
0
12
6
0
0
0
6
6
0
24
12
18
0
24
12
% S
% Thr:
0
6
12
0
12
0
0
6
0
0
6
6
0
0
0
% T
% Val:
6
0
0
0
6
0
0
0
0
0
0
6
12
0
6
% V
% Trp:
36
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% W
% Tyr:
0
0
0
6
0
6
0
48
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _